PRECONDITIONING LOCAL INJECTION OF ACTIVATED PLATELET-RICH PLASMA INCREASES ANGIOGENESIS, VEGF LEVELS, AND VIABILITY OF MODIFIED MCFARLANE FLAP IN DIABETES-INDUCED RATS

Preconditioning Local Injection of Activated Platelet-Rich Plasma Increases Angiogenesis, VEGF Levels, and Viability of Modified McFarlane Flap in Diabetes-Induced Rats

Background The risk of flap necrosis in tissue reconstruction surgery is elevated in patients with vascular disorders, such as diabetes mellitus.Chronic hyperglycemia causes endothelial cell SUPER MULTI-WITH IRON dysfunction and increases inflammatory process, causing vascular insufficiency.Platelet-rich plasma (PRP) contains high levels of platele

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