Preconditioning Local Injection of Activated Platelet-Rich Plasma Increases Angiogenesis, VEGF Levels, and Viability of Modified McFarlane Flap in Diabetes-Induced Rats
Background The risk of flap necrosis in tissue reconstruction surgery is elevated in patients with vascular disorders, such as diabetes mellitus.Chronic hyperglycemia causes endothelial cell SUPER MULTI-WITH IRON dysfunction and increases inflammatory process, causing vascular insufficiency.Platelet-rich plasma (PRP) contains high levels of platele